Paste a list of genes in the box provided.

Paste a list of genes in the box

"Genes" pipeline allows a query of genes of interest against LINCS data. One may start a query by inputing a list of genes via Entrez gene IDs or gene symbols separated by comma in the search field and clicking "Search for set of gene symbols or IDs". This section describes how to submit your own list of genes for analysis.

The figure above shows the screen to submit your own list of genes. You can use either entrez ids (e.g. 2099) or symbols (e.g. esr1). As shown in the figure, type/paste a list in the box. Let's input genes 10,12,2099 in the box and click "Search for set of gene symbols or IDs".

At this point our database is searched for all the genes submitted and the figure above shows the list of genes found. To analyze gene(s) select genes of interest and then click "Analyze with X genes". The figure below is a screenshot listing LINCS and non-LINCS datasets available for analysis (default view is listing all LINCS datasets, but you may explore other datasets by selecting tab "All Datasets" and explore available pre-computed signatures by selecting the tab "Signatures"). Please, select a LINCS dataset of interest and click "Analyze" as seen in the figure below.

Your gene list will be queried against all LINCS datasets and the results screen will display all of the datasets on iLINCS portal. As seen in the figure above, "Genes" column indicates the number of genes from your query that was found in a particular dataset. Only datasets with at least one found gene will be available for the analysis.  

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